Search Result

Search Results for " interferon β "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T13736	Interferon receptor inducer-1		IFNAR
	Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer.		IFNAR
T12933	SM-276001		TLR , COX
	SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.		TLR , COX
T8798	MSA-2		STING
	MSA-2 is a potent and orally available non-nucleotide STING agonist.		STING
T14687	Deucravacitinib	BMS-986165	Tyrosine Kinases , JAK , IFNAR , Interleukin
	Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively bi...		Tyrosine Kinases , JAK , IFNAR , Interleukin
T11630	IFN alpha-IFNAR-IN-1 hydrochloride		Others , IFNAR
	IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.		Others , IFNAR
T7081	CCCP	Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone	Apoptosis , IκB/IKK , COX , Mitochondrial Metabolism , STING , IFNAR , Antibacterial
	CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules ...
T5317	Cridanimod	CMA,XBIO-101,10-carboxymethyl-9-acridanone	Progesterone Receptor , STING , IFNAR
	Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.		Progesterone Receptor , STING , IFNAR
T4403	AX-024 hydrochloride	AX-024 HCl	IL Receptor , TNF , COX , IFNAR , Interleukin
	AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.		IL Receptor , TNF , COX , IFNAR , Interleukin
T22142	RO8191	RO4948191,CDM-3008	HCV Protease , HBV , JAK , IFNAR , STAT
	RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.		HCV Protease , HBV , JAK , IFNAR , STAT
T6273	Vadimezan	DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus , VDA , STING , IFNAR
	Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff...		Influenza Virus , VDA , STING , IFNAR
T26895	BRD0476	BRD-0476,ML 187,ML187,ML-187,BRD 0476
	BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell ...
T76930	Bifarcept
	Bifarcept, a recombinant antibody targeting the interferon receptor type I (IFN-RI), enhances the serum half-life of IFN-β by facilitating its binding.
T38162	STING18
	STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 μM in a radioligand binding assay).1 It inhibits cGAMP-induced IFN-β production (IC50 = 11 μM) but does not stimulate IFN-β productio...
T73693	Peginterferon beta-1a
	Peginterferon beta-1a (Peginterferon β-1a), the inaugural pegylated interferon beta-1a derivative, promotes apoptosis in cancer cells and exhibits anti-tumor properties in nude mice models. It is utilized in the study of...
T35654	2'2'-cGAMP (sodium salt)
	2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. It binds to the adapter protein stimulator of interferon genes , which is a component of the innate immune response that...
T10065	2',3'-cGAMP	2'-3'-cyclic GMP-AMP	STING , cGAS
	2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP binds to STING to form a dimer, inducing the produc...		STING , cGAS
T38091	3'3'-cGAMP (sodium salt)
	3'3'-cGAMP is a second messenger produced in bacteria by specific dinucleotide cyclases. It contains canonical 3'5'-phosphodiester bonds and regulates chemotaxis, colonization, and other cellular functions. 3'3'-cGAMP sh...
T38160	STING Agonist 1a
	STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expres...
T38158	StA-IFN-1
	StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN ind...
T36461	CAY10748	CAY10748
	CAY10748 is an agonist of stimulator of interferon genes (STING; IC50= 0.3794 μM in a competition binding assay).1It activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 μM, re...
T38161	STING Agonist C11	STING Agonist C11
	STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphory...
T83841	STING Agonist D61	D61,Stimulator of Interferon Genes Agonist D61
	STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline phosphatase (SEAP) and IFN-β-inducible reporter genes in cellular as...
T83775	STING Agonist 12L	Stimulator of Interferon Genes Agonist 12L
	STING agonist 12L is a stimulator of interferon genes (STING) agonist that exhibits binding affinity for both wild-type STING and its variants R232, AQ, and Q with half-maximal inhibitory concentrations (IC50s) of 1.15 µ...

Compounds

Interferon receptor inducer-1

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

IFN alpha-IFNAR-IN-1 hydrochloride

T11630

Synonym:

Target: Others, IFNAR

CCCP

T7081

Synonym: Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone

Target: Apoptosis, IκB/IKK, COX, Mitochondrial Metabolism, STING, IFNAR, Antibacterial

Cridanimod

T5317

Synonym: CMA,XBIO-101,10-carboxymethyl-9-acridanone

Target: Progesterone Receptor, STING, IFNAR

AX-024 hydrochloride

T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

RO8191

T22142

Synonym: RO4948191,CDM-3008

Target: HCV Protease, HBV, JAK, IFNAR, STAT

Vadimezan

T6273

Synonym: DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Target: Influenza Virus, VDA, STING, IFNAR

BRD0476

T26895

Synonym: BRD-0476,ML 187,ML187,ML-187,BRD 0476

Peginterferon beta-1a

T73693

Synonym:

Target:

2'2'-cGAMP (sodium salt)

Synonym: 2'-3'-cyclic GMP-AMP

Target: STING, cGAS

3'3'-cGAMP (sodium salt)

Synonym: STING Agonist C11

Target:

STING Agonist D61

T83841

Synonym: D61,Stimulator of Interferon Genes Agonist D61

Target:

STING Agonist 12L

T83775

Synonym: Stimulator of Interferon Genes Agonist 12L

Target:

Cat No.	Product Name	Synonyms	Targets
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
T14854	Caerulomycin A	Cerulomycin,Caerulomycin	Antifungal
	Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antif...		Antifungal

Natural Products

Ginsenoside F3

T3829

Synonym:

Target: Others, IFNAR, Interleukin

Caerulomycin A

T14854

Synonym: Cerulomycin,Caerulomycin

Target: Antifungal

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00831	IFN-beta Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IFN-beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is A0A7R8GV38.
TMPY-03145	IFN-beta Protein, Human, Recombinant	Human	CHO Cells
	IFN-beta Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 20 kDa and the accession number is P01574.
TMPY-03467	IFN-beta Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.3 kDa and the accession number is P01575.
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPY-03828	IFN-beta Protein, Rhesus, Recombinant (mFc)	Rhesus	HEK293 Cells
	IFN-beta Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7NFX1.
TMPY-04254	IFNAR1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.7 kDa and the accession number is H9Z8H4.
TMPY-00139	IFNAR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IFNAR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is XP_005548871.1.
TMPY-03927	IFNAR1 Protein, Rhesus, Recombinant	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 48.3 kDa and the accession number is H9Z8H4.
TMPY-03829	IFNAR1 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is H9Z8H4.
TMPY-02456	IFN-beta Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is P01575.
TMPY-01489	IFNAR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is P33896.
TMPY-01640	IFNAR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPY-01642	IFNAR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-02634	IFNAR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74 kDa and the accession number is P17181-1.
TMPJ-00331	IFNAR1 Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
	Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-...
TMPJ-00780	IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interfer...
TMPJ-01371	Limitin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin...